Accelerate with care
As you probably already know, stopping for whatever reason will end the current level. The accelerate button is the most important one and you should never move your finger too far away from it. However, you should take it easy when going downhill or when on the air because the physics system will take care of everything for you. The decision between conserving fuel or going faster is a crucial one but unobstructed paths are prime opportunities to take it easy with acceleration.
Use the rotation buttons sparingly
Because Earn to Die 2 is a physics-based at its core, the rotation buttons are extremely important. Light touches are instrumental in letting you climb hills, crash through obstacles and kill those nasty zombies. If you are not careful, however, your car can easily flip and there is a very good chance you will damage a part. This is especially true in certain locations like tunnels as my trigger-happy fingers got me stuck in more than one occasion with my car backwards and my dreams crushed. Do not let the same thing happen to you.